GLP1 - Mechanism of Action
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YouTubeDr Rakesh SONAWANE
GLP1 - Mechanism of Action
All GLP-1 receptor agonists share a common mechanism, activation of the GLP-1 receptor. GLP-1 receptors are expressed by β cells, cells in the peripheral and central nervous systems, the heart and vasculature, kidney, lung, and GI mucosa. Binding of agonists to the GLP-1 receptor activates the cyclic AMP-PKA pathway and several GEFs (guanine ...
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