Background The development of IBD is known to involve early immunological alterations, but our understanding of the changes ...

Randomised controlled trials (RCTs) have shown that computer-aided detection (CADe) can significantly improve adenoma detection rates (ADRs). In contrast, implementation studies did not show ADR ...

Introduction The Covid-19 pandemic severely disrupted healthcare services. In March 2020, the government announced the ‘Everyone In’ initiative to support everyone rough sleeping or in accommodation ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

A high adenoma detection rate (ADR) is vital for effective colorectal cancer (CRC) screening, but evidence suggests limited additional benefit beyond a certain threshold. In a pooled analysis of five ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

Conclusion Managing the demands of insourcing in an efficient and safe way is a challenge. Prior to introduction of the VIEC, our unit allocated 4 hours of consultant time for every 2 days of ...

Introduction Although chloradiazepoxide remains the drug of choice in alcohol withdrawal syndrome (AWS), lorazepam or Oxazepam is considered a safer option in patients with decompensated liver ...

Results Between 01/01/2023 and 31/12/2024, 580 patients were enrolled in the HCC surveillance program. Of these, 398 patients were included in the audit, based on the availability of data. A total of ...

Objective Gastric adenocarcinoma (gastric cancer, GC) is a major cause of global cancer mortality. Identifying molecular programmes contributing to GC patient survival may improve our understanding of ...

Background The earliest endoscopically-evident lesion in Crohn's disease is the aphthous ulcer, which develops over ectopic lymphoid tissues (ie, inducible lymphoid follicles (ILF), tertiary lymphoid ...

Conclusion This study highlights the impact of the COVID pandemic on mortality of patients with known alcohol related cirrhosis seen in the specialist outpatient clinic. Mortality increased despite ...