We thank the patient and his family for their participation in this study; all the persons involved in the rapid manufacturing and evaluation of k-abe, including Kamila Wlodarczyk, Nicholas Tougas ...

Most moderate-to-late–preterm infants need nutritional support after birth pending a sufficient supply and intake of mother’s breast milk; however, evidence for the best strategy for nutrition ...

The International Agency for Research on Cancer (IARC) classified alcoholic beverages as carcinogenic to humans (Group 1) on the basis of sufficient evidence of causality for seven types of cancer ...

The androgen-receptor inhibitors apalutamide and enzalutamide have recently been approved for the treatment of nonmetastatic, castration-resistant prostate cancer on the basis of phase 3 trials ...

Shown are the genetic variants identified in EPO, the gene encoding erythropoietin (EPO), in patients with erythrocytosis. The term cDNA denotes complementary DNA, F female, M male, and NA not ...

The β 2 common integrin subunit CD18 is essential for leukocyte–endothelial adhesion and extravasation to inflamed or infected tissue. Damaging variants in ITGB2, which encodes CD18, cause ...

These epidemiologic patterns highlight the limitations of focusing on genetics alone. Although the Human Genome Project greatly expanded our understanding of hereditary contributions to disease ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

Of the 1404 teenage girls and women enrolled in CHOICE, 72% chose an intrauterine device or implant (LARC methods); the remaining 28% chose another method. During the 2008–2013 period, the mean ...

Studies that evaluated adjunctive glucocorticoids for the treatment of various forms of tuberculosis showed reduced mortality among patients with tuberculous meningitis and fewer complications ...

Inadequate payment is just one of many factors that negatively affect daily practice and contribute to burnout among primary care physicians. Also problematic are growing piles of nonclinical tasks.

Intervention to reduce the levels of circulating low-density lipoprotein (LDL) cholesterol and its major protein, apolipoprotein B, is one of the most effective ways to reduce the risk of cardiovas ...