Objective Antibodies against contactin-associated protein-like 2 (CASPR2-Abs) have been described in acquired neuromyotonia, limbic encephalitis (LE) and Morvan syndrome (MoS). However, it is unknown ...

Background and purpose To investigate early clinical surrogates for long-term independency of patients treated with thrombectomy for large vessel occlusion stroke in daily clinical routine. Methods ...

Background Anti-N-methyl-D-aspartate receptor encephalitis (NMDARE) is a severe autoimmune disorder with high morbidity and mortality. Current treatments have limitations including relapse, ...

Correspondence to Professor Piero Parchi, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale, Università di Bologna, Bologna 40138, Italy; piero.parchi{at}unibo.it Objective To compare ...

Institute for Neuroradiology, JW Goethe-University Frankfurt am Main, Frankfurt, Germany Dr Oliver Singer, Department of Neurology, JW Goethe-University Frankfurt am Main, Schleusenweg 2-16, D-60528 ...

Objectives The placement of an external ventricular drain (EVD) is a common neurosurgical operation that carries great benefit in acute hydrocephalus but is not without risk. In our centre, bolt EVDs ...

The objective of this paper is to evaluate available evidence for each step in autoimmune encephalitis management and provide expert opinion when evidence is lacking. The paper approaches autoimmune ...

Cerebral lesions may alter the capability of bilingual subjects to separate their languages and use each language in appropriate contexts. Patients who show pathological mixing intermingle different ...

Correspondence to Dr Christine Lo, Department of Clinical Neurosciences, University of Oxford Nuffield, Oxford OX1 1NF, Oxfordshire, UK; christine.lo{at}nhs.net Background An unmet need remains for ...

Background To evaluate the efficacy of rituximab in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients not responding to conventional immune therapies. Methods An open-label, ...

Spinal arachnoiditis is a rare condition. Eighty cases, diagnosed during a period when 7600 spinal contrast investigations were undertaken, have been reviewed. The majority had suffered a previous ...

Objective To establish a rigorous, expert-led, evidence-based approach to the evaluation of licensed drugs for repurposing and testing in clinical trials of people with progressive multiple sclerosis ...