Cleveland Guardians first baseman Carlos Santana was scratched from the lineup against the Detroit Tigers with tightness in his left leg.

Kyle Manzardo started the 10th with a double into the left field corner off Brenan Hanifee (2-2) to score Ramirez, the automatic runner at second, for a 4-3 lead. After Carlos Santana walked, Angel Martinez doubled to score Manzardo. A sacrifice fly by Bo Naylor and single by Nolan Jones ended the scoring.

The Cleveland Guardians (29-22) look to complete a 4-game sweep at the Detroit Tigers (33-20) Sunday. First pitch from Comerica Park is set for 11:35 a.m. ET (Roku). Let's analyze BetMGM Sportsbook's MLB odds around the Guardians vs. Tigers odds and make our expert MLB picks and predictions for the best bets.

It felt like the Tigers were waiting around to die Saturday night. Finally, in the 10th inning, the Guardians obliged them.

Will the Detroit Tigers pick up their MLB-leading 34th win of the season? Here are the best bets from the SportsLine Projection Model

Cleveland Guardians' José Ramírez, right, slides safely into home plate ahead of a tag by Detroit Tigers catcher Jake Rogers, left, to tie a bseball game in the eighth inning Saturday, May 24, 2025, in Detroit. (AP Photo/Lon Horwedel) AP

On Saturday, Cleveland won its fifth straight game against the Tigers between regular season and postseason play. Amazingly, the Guardians' 7–5 10-inning victory tied the all-time series at 1,161 games apiece. Sunday is the rubber match, and as all baseball fans know, the six best words in sports are Game Two Thousand Three Hundred Thirty-Five.