On their own, these observations are consistent with other reports published during the last few years suggesting a potential link between mTORC1 and SREBP-1c–mediated lipid biosynthesis (9).

Preventing pathogenic viral and bacterial transmission in the human environment is critical, especially in potential outbreaks that may be caused by the release of ancient bacteria currently trappe ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Efforts to anticipate and adapt to future climate can benefit from historical experiences. We examine agroclimatic conditions over the past 50 y fo ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans ...

The global transport of heat and momentum in turbulent convection is constrained by thin thermal and viscous boundary layers at the heated and cool ...

By using titin as a model system, we have demonstrated that fluorescence quenching can be used to study protein folding at the single molecule le ...

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The phenomenon of benign overfitting is one of the key mysteries uncovered by deep learning methodology: deep neural networks seem to predict well, even with a perfect fit to noisy training data.

With scientific integrity and responsibility in mind, the National Academy of Sciences, the Annenberg Public Policy Center of the University of Pennsylvania, and the Annenberg Foundation Trust at ...

Extracellular redox-active compounds, flavins and other quinones, have been hypothesized to play a major role in the delivery of electrons from cel ...

Membrane proteins are encoded by 20–35% of genes but represent <1% of known protein structures to date. Thus, improved methods for membrane-protein structure determination are of critical importance.